Monday, August 29, 2011

Neonates and Midazolam/Versed

I googled "neonates Midazolam" this morning and found this study, right off the bat. Intravenous midazolam infusion for sedation of infants in the neonatal intensive care unit

Here is the summary;
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Plain language summary



Intravenous midazolam infusion for sedation of infants in the neonatal intensive care unit







There is no evidence to show the benefit of midazolam as a sedative for newborn babies in neonatal intensive care. Newborn babies undergoing uncomfortable procedures in intensive care units may need sedation to reduce stress and avoid complications. It is difficult to measure their pain so sedatives or pain killers are sometimes overlooked for newborn babies. Midazolam is a short acting sedative increasingly used in neonatal intensive care. The review of trials found no evidence to support the use of midazolam as a sedative for neonates undergoing intensive care. Babies receiving midazolam stayed in hospital longer and had more adverse effects. More research is needed to address the safety and effect of midazolam.



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"THERE IS NO EVIDENCE TO SHOW THE BENEFIT OF MIDAZOLAM AS A SEDATIVE FOR NEWBORN BABIES IN NEONATAL INTENSIVE CARE." That's pretty plain language! "BABIES RECEIVING MIDAZOLAM STAYED IN THE HOSPITAL LONGER AND HAD MORE ADVERSE EFFECTS." I wonder if they have studied the effects on the babies BRAINS? There are other studies which say that pregnant or nursing WOMEN should NOT get Versed/Midazolam lest it adversely effect their babies, either through the bloodstream or through the breast milk.


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