Sunday, May 23, 2010


Here is a blurb from a study done in the UK where patients WERE routinely injected with Midazolam in the ICU. (italics mine)

These findings have led to a change in prescribing practice in our ICU. We no longer use midazolam for sedation, and our sedation policy is now based on administering propofol or lorazepam. This view is also supported by the Society of Critical Care Medicine's most recently published guidelines [10], which recommend use of lorazepam for sedating most patients via intermittent or continuous infusion and use of propofol for short-term sedation, and that midazolam be reserved for rapid control of agitated patients and for short-term sedation. As a consequence, we were unable to conduct a more formal study of midazolam's role in over-sedation or extend the study to a larger group of patients.

Here is the full text;Critical Care Full text Differentiating midazolam over-sedation from neurological damage in the intensive care unit

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